Ipamorelin

GH/GHRH FDA Approved

Growth hormone releasing peptide (GHRP)

Mechanism of Action

Stimulates ghrelin receptors to release growth hormone. Considered one of the mildest GHRPs with fewer side effects.

253
Community Posts
112
Users Discussing
1
Research Articles

Reported Outcomes

Clinical Strength: D

Based on community reports (253 posts). Grade reflects frequency and consistency of positive mentions.

D Body Composition
61 mentions

Changes in muscle vs fat ratio

D Sleep Quality
42 mentions

Effects on sleep quality

D Weight Loss
25 mentions

Reduction in body weight

D Appetite Suppression
18 mentions

Reduced hunger and food cravings

D Mental/Mood
20 mentions

Effects on mood and cognitive function

D Blood Sugar Control
15 mentions

Improved glycemic control and insulin sensitivity

D Energy Levels
14 mentions

Changes in energy and fatigue levels

D Cardiovascular
6 mentions

Effects on heart health markers

Side Effects

Based on 71 user reports. Frequency indicates how often each was mentioned.

Common (>5%)

Fatigue
Mild 10 reports 11.0%
Water Retention
Mild 9 reports 9.9%
Constipation
Mild 8 reports 8.8%
Insomnia
Mild 8 reports 8.8%
Nausea
Mild 7 reports 7.7%
Stinging
Mild 7 reports 7.7%
Tiredness
Mild 5 reports 5.5%

Uncommon (1-5%)

Hair Loss
Mild 4 reports 4.4%
Heartburn
Mild 4 reports 4.4%
Lethargy
Mild 3 reports 3.3%
Food Noise
Mild 3 reports 3.3%
Burning
Mild 3 reports 3.3%
Muscle Loss
Mild 3 reports 3.3%
Acid Reflux
Mild 3 reports 3.3%
Injection Site Pain
Mild 3 reports 3.3%
Appetite Suppression
Mild 3 reports 3.3%
Edema
Mild 2 reports 2.2%
Binge Eating
Mild 2 reports 2.2%
Injection Site Reaction (Isr)
Mild 2 reports 2.2%
Pain
Mild 2 reports 2.2%

Risks & Warnings

Important safety considerations based on clinical data and community reports.

!

Muscle Loss

7 mentions

Rapid weight loss may include muscle. Adequate protein intake and resistance training recommended.

!

Hypoglycemia Risk

5 mentions

Risk increases when combined with insulin or sulfonylureas. Monitor blood sugar carefully.

!

Psychiatric Effects

4 mentions

Monitor for mood changes. Report any concerning psychiatric symptoms to healthcare provider.

i

Injection Site Reactions

4 mentions

Local reactions are common and usually mild. Rotate injection sites.

Dosing

Standard Protocol

Starting Dose
100-300mcg 2-3x daily
Titration
No established protocol
Half-life
~2 hours
Administration
Subcutaneous injection

Community Dosing Patterns

Based on 97 mentions

Community-reported patterns, not medical advice.

250mcg daily
4
200mcg daily
3
100mcg daily
3
daily
2
5 days on/2 days off
2

Pricing

Research-grade reference pricing for 10mg vial. Prices vary by vendor and quantity.

We do not list vendors. Prices are aggregated from community reports and should be treated as rough ranges.

US Research Grade

$70

Single small vial from US domestic vendors

US Research Grade (Bulk)

$39.2

Per-dose equivalent when buying larger US vials

China Research Grade

$6

Per-vial when buying 10-pack from Chinese vendors

91% savings

Research

1
Total Articles
0 0

Key Studies

Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics Preclinical

J Exp Pharmacol (2020)

Commonly Stacked With

Based on 253 community posts mentioning Ipamorelin.

Tesamorelin 93 mentions (36.8%)
CJC-1295 52 mentions (20.6%)
Retatrutide 33 mentions (13%)
Tirzepatide 21 mentions (8.3%)
TB-500 20 mentions (7.9%)

Switching Patterns

Based on 24 discussions about switching to or from Ipamorelin.

→ Switching FROM

Retatrutide 6 mentions

Users who switched to Ipamorelin

← Switching TO

Retatrutide 4 mentions

Users who switched from Ipamorelin

Frequently Asked Questions

What is ipamorelin?

Does ipamorelin stimulate growth hormone release?

Can CJC-1295 and ipamorelin be combined?

Does ipamorelin improve sleep quality?

What are the side effects of ipamorelin?